An introduction to probabilistic model building (or thinking about models in the era of AI) – Biomics An introduction to probabilistic model building (or thinking about models in the era of AI) – Biomics

An introduction to probabilistic model building (or thinking about models in the era of AI)

Trainers:

Mafalda Dias and Jonathan Frazer are group leaders at the CRG, Barcelona, where they co-lead the Probabilistic Machine Learning and Genomics group.

They develop deep learning and probabilistic modeling approaches applied to genomics and other large-scale multimodal biological data to address questions in disease genetics, protein function and conservation genomics.

Course objective:

This course aims to develop a principled understanding of probabilistic model building in the context of modern AI, equipping participants to reason under uncertainty, integrate prior knowledge, and construct interpretable, data-efficient models. It encourages a shift from purely data-driven approaches to more structured and hypothesis-aware modelling, supporting better decision-making and experimental design.

Learning outcomes:

  • Apply probabilistic reasoning to model building in AI
  • Incorporate prior knowledge into structured, interpretable models
  • Understand key probabilistic approaches in modern machine learning
  • Design more efficient experiments using active learning principles
  • Critically assess modelling assumptions and limitations

What to bring:

  • A laptop
  • Active Gmail account (we will use Google Collab environments)